63: Mechanism of fructose-induced hyperuricemia
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چکیده
منابع مشابه
Fructose-Induced Hyperuricemia Is Associated With a Decreased Renal Uric Acid Excretion in Humans
Ingestion of a high-fructose meal increases blood uric acid (UA) concentration in healthy subjects (1). Furthermore, high-fructose intake over several days is associated with increased fasting UA concentration (1). These effects are generally attributed to an increased UA production, as observed after intravenous fructose administration (2). It has not been assessed, however, whether UA also in...
متن کاملAstilbin attenuates hyperuricemia and ameliorates nephropathy in fructose-induced hyperuricemic rats.
Astilbin is a flavonoid compound isolated from the rhizome of Smilax china L. The effects and possible mechanisms of astilbin on hyperuricemia and nephropathy rats were elucidated in this study. Different dosages of astilbin (1.25, 2.5, and 5.0 mg/kg) were administered to 10 % fructose-induced hyperuricemic rats. The results demonstrated that astilbin significantly decreased the serum uric acid...
متن کاملEffect of Vanadyl Sulfate on Fructose-Induced Insulin Resistance Rat
Insulin resistance syndrome, also referred to as the metabolic syndrome or syndrome X, refers to a constellation of common metabolic and cardiovascular disorders (e.g. obesity, type 2 diabetes mellitus, hypertension, and dyslipidemia), which are all cardiovascular risk factors. Insulin resistance can be induced by fructose-rich diet in rats. We investigated the effect of vanadyl sulfate (0.2 mg...
متن کاملAllopurinol, rutin, and quercetin attenuate hyperuricemia and renal dysfunction in rats induced by fructose intake: renal organic ion transporter involvement
Hyperuricemia and gout appear to be rapidly increasing worldwide and frequently cause symptoms of metabolic syndrome. Dietary flavonoids have their potential beneficial effects on human health. In the present study, 15 flavonoids (quercetin, morin, myricetin, kaempferol, icariin, apigenin, luteolin, baicalin, silibinin, naringenin, formonoetin, genistein, puerarin, daidzin and naringin dihydroc...
متن کاملAllopurinol, rutin, and quercetin attenuate hyperuricemia and renal dysfunction in rats induced by fructose intake: renal organic ion transporter involvement.
Fructose consumption has been recently related to an epidemic of metabolic syndrome, and hyperuricemia plays a pathogenic role in fructose-induced metabolic syndrome. Fructose-fed rats showed hyperuricemia and renal dysfunction with reductions of the urinary uric acid/creatinine ratio and fractional excretion of uric acid (FE(ur)), as well as other features of metabolic syndrome. Lowering serum...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1976
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197610000-00060